Estimates in-hospital KRT needed in patients admitted for COVID-19.
When to use?
At admission in the hospital, to stratify the in-hospital KRT needed risk of COVID-19 patients.
How was it developed and validated?
Based in a cohort of 5,212 patients from 35 hospitals, from 17 cities in Brazil,following strict methodological criteria.
Why to use?
How it should be used?
Only in-hospital patients, through the use of variables easily accessible at admission.
How it should not be used?
Variable | MMCD Score | |
---|---|---|
$M$ | $M$echanical ventilation anytime during hospital stay$^a$ | |
No | 0 | |
Yes | 11 | |
$M$ | $M$ale sex | |
No | 0 | |
Yes | 1 | |
$C$ | $C$reatinine (mg/dL) upon hopistal presentation | |
$\lt$ 1.2 | 0 | |
1.2 - 2.0 | 1 | |
2.0 - 3.5 | 2 | |
3.5 - 5.0 | 4 | |
$\geqslant$ 5.0 | 10 | |
$D$ | $D$iabetes mellitus | |
No | 0 | |
Yes | 1 |
Flávio de Azevedo Figueiredo$^{1,2}$, Lucas Emanuel Ferreira Ramos$^3$, Rafael Tavares Silva$^3$, Magda Carvalho Pires$^3$, Daniela Ponce$^{4}$, Rafael Lima Rodrigues de Carvalho$^{24}$, Alexandre Vargas Schwarzbold$^5$, Amanda de Oliveira Maurílio$^6$, Ana Luiza Bahia Alves Scotton$^7$, Andresa Fontoura Garbini$^8$, Bárbara Lopes Farace$^9$, Bárbara Machado Garcia$^{10}$, Carla Thais Cândida Alves da Silva$^{11}$, Christiane Corrêa Rodrigues Cimini$^{12,13}$, Cíntia Alcantara de Carvalho$^{14}$, Cristiane dos Santos Dias$^{15}$, Daniel Vitorio Silveira$^{16}$, Euler Roberto Fernandes Manenti$^{17}$, Evelin Paola de Almeida Cenci$^{18}$, Fernando Anschau$^{18}$, Fernando Graça Aranha$^{19}$, Filipe Carrilho de Aguiar$^{20}$, Frederico Bartolazzi$^{11}$, Giovanna Grunewald Vietta$^{19}$ MD, Guilherme Fagundes Nascimento$^{16}$, Helena Carolina Noal$^{5}$, Helena Duani$^{21}$, Heloisa Reniers Vianna$^{22}$, Henrique Cerqueira Guimarães$^{9}$, Joice Coutinho de Alvarenga$^{14}$, José Miguel Chatkin$^{23}$, Júlia Parreiras Drumond de Moraes$^{22}$, Juliana Machado Rugolo$^{4}$, Karen Brasil Ruschel$^{17,24}$, Karina Paula Medeiros Prado Martins$^{21, 24}$, Luanna Silva Monteiro Menezes$^{25,26}$, Luciana Siuves Ferreira Couto$^{25}$, Luís César de Castro$^{28}$, Luiz Antônio Nasi$^{27}$, Máderson Alvares de Souza Cabral$^{21}$, Maiara Anschau Floriani$^{27}$, Maíra Dias Souza$^{26}$, Maira Viana Rego Souza e Silva$^{1}$, Marcelo Carneiro$^{29}$, Mariana Frizzo de Godoy$^{23}$, Maria Aparecida Camargos Bicalho$^{10}$, Maria Clara Pontello Barbosa Lima$^{30}$ , Matheus Carvalho Alves Nogueira$^{31}$, Matheus Fernandes Lopes Martins$^{32}$, Milton Henriques Guimarães Júnior$^{32}$, Natália da Cunha Severino Sampaio$^{33}$, Neimy Ramos de Oliveira$^{33}$, Patricia Klarmann Ziegelmann$^{24,34}$, Pedro Guido Soares Andrade$^{35}$, Pedro Ledic Assaf$^{36}$, Petrônio José de Lima Martelli$^{20}$, Polianna Delfino Pereira$^{1,14}$, Raphael Castro Martins$^{34}$, Rochele Mosmann Menezes$^{29}$, Saionara Cristina Francisco$^{36}$, Silvia Ferreira Araújo$^{35}$, Talita Fischer Oliveira$^{26}$, Thainara Conceição de Oliveira$^{18}$, Thaís Lorenna Souza Sales$^{24,37}$, Yuri Carlotto Ramires$^{28}$, Milena Soriano Marcolino$^{1,21,24,38}$
$^1$Department of Internal Medicine, Medical School, Universidade Federal de Minas Gerais. Av. Professor Alfredo Balena, 190, Belo Horizonte, Brazil. $^{2}$Department of Medicine, Universidade Federal de Lavras. Aquenta Sol, Lavras, Brazil. $^{3}$Department of Statistics, Universidade Federal de Minas Gerais. Av. Presidente Antônio Carlos, 6627, Belo Horizonte, Brazil. $^{4}$Botucatu Medical School, Universidade Estadual Paulista “Júlio de Mesquita Filho”. Av. Prof. Mário Rubens Guimarães Montenegro, Botucatu, Brazil. $^{5}$Hospital Universitário de Santa Maria. Av. Roraima, 1000, Santa Maria, Brazil. $^{6}$Hospital São João de Deus. R. do Cobre, 800, Divinópolis, Brazil. $^{7}$Hospital Regional Antônio Dias. R. Maj. Gote, 1231, Patos de Minas, Brazil. $^{8}$Hospital Nossa Senhora da Conceição and Hospital Cristo Redentor. Av. Francisco Trein, 326, Porto Alegre, Brazil. $^{9}$Hospital Risoleta Tolentino Neves. R. das Gabirobas, 01, Belo Horizonte, Brazil. $^{10}$0Hospital Júlia Kubitschek. Av. Professor Alfredo Balena, 190, Belo Horizonte, Brazil. $^{11}$1Hospital Santo Antônio. Praça Dr. Márcio Carvalho Lopes Filho, 501, Curvelo, Brazil. $^{12}$Hospital Santa Rosália. R. do Cruzeiro, 01, Teófilo Otoni, Brazil. $^{13}$Mucuri Medical School, Universidade Federal dos Vales do Jequitinhonha e Mucuri. R. Cruzeiro, 01, Teófilo Otoni, Brazil. $^{14}$Hospital João XXIII. Av. Professor Alfredo Balena, 400, Belo Horizonte, Brazil. $^{15}$Department of Pediatrics, Medical School, Universidade Federal de Minas Gerais. Av. Professor Alfredo Balena, 190, Belo Horizonte, Brazil. $^{16}$Hospital UNIMED BH. Av. do Contorno, 3097, Belo Horizonte, Brazil. $^{17}$Hospital Mãe de Deus. R. José de Alencar, 286, Porto Alegre, Brazil. $^{18}$Hospital Universitário Canoas. Av. Farroupilha, 8001, Canoas, Brazil. $^{19}$Hospital SOS Cárdio. Rodovia, SC-401, 121, Florianópolis, Brazil. $^{20}$Hospital das Clínicas da Universidade Federal de Pernambuco. Av. Prof. Moraes Rego, 1235, Recife, Brazil. $^{21}$Medical School and University Hospital, Universidade Federal de Minas Gerais. Avenida Professor Alfredo Balena, 190, Belo Horizonte, Brazil. $^{22}$Hospital Universitário Ciências Médicas. R. dos Aimorés, 2896, Belo Horizonte, Brazil. $^{23}$Hospital São Lucas da PUCRS. Av. Ipiranga, 6690, Porto Alegre, Brazil. $^{24}$Institute for Health Technology Assessment (IATS/ CNPq). R. Ramiro Barcelos, 2359, Porto Alegre, Brazil. $^{25}$Hospital Luxemburgo. R. Gentios, 1350, Belo Horizonte, Brazil. $^{26}$Hospital Metropolitano Odilon Behrens. R. Formiga, 50, Belo Horizonte, Brazil. $^{27}$Hospital Moinhos de Vento. R. Ramiro Barcelos, 910, Porto Alegre, Brazil. $^{28}$Hospital Bruno Born. Av. Benjamin Constant, 881, Lajeado, Brazil. $^{29}$Hospital Santa Cruz. R. Fernando Abott, 174, Santa Cruz do Sul, Brazil. $^{30}$Medical School, Universidade Federal de Ouro Preto. R. Diogo de Vasconcelos, 122, Ouro Preto, Brazil. $^{31}$Hospitais da Rede Mater Dei. Av. do Contorno, 9000, Belo Horizonte, Brazil. $^{32}$Hospital Márcio Cunha. Av. Kiyoshi Tsunawaki, 48, Ipatinga, Brazil. $^{33}$Hospital Eduardo de Menezes. R. Dr. Cristiano Rezende, 2213, Belo Horizonte, Brazil. $^{34}$Hospital Tacchini. R. Dr. José Mário Mônaco, 358, Bento Gonçalves, Brazil. $^{35}$Hospital Semper. Alameda Ezequiel Dias, 389, Belo Horizonte, Brazil. $^{36}$Hospital Metropolitano Doutor Célio de Castro. R. Dona Luiza, 311, Belo Horizonte, Brazil. $^{37}$Universidade Federal de São João del-Rei. R. Sebastião Gonçalves Coelho, 400, Divinópolis, Brazil. $^{38}$Telehealth Center, University Hospital, Universidade Federal de Minas Gerais. Av. Professor Alfredo Balena, 110, Belo Horizonte, Brazil.